NBA DFS: Top DraftKings, FanDuel daily Fantasy basketball picks for Wednesday, November 6 include LeBron James

SportsLine's Mike McClure, a daily Fantasy pro with more than $2 million in winnings, gives optimal NBA DFS lineup advice for Wednesday, Nov. 6

Paul George (knee) is probable to play in his return to Los Angeles after making his Philadelphia 76ers debut on Monday. George, who signed a four-year, $212 million deal with the 76ers this offseason, had 15 points, five rebounds and four assists over 32 minutes on Monday against Kevin Durant and the Suns. Now he'll face James Harden and the Clippers, the team he spent the last five seasons with, so should daily Fantasy basketball players expect more minutes and production from George when making NBA DFS lineups?

Joel Embiid (suspension) remains out, so he won't be a part of the Wednesday NBA DFS player pool. But Embiid's absence gives George the chance for a larger role, and Andre Drummond's averaging 8.5 points and 10.7 rebounds without Embiid, so the 76ers big man should be a consideration in your NBA DFS strategy. Before making any NBA DFS picks, be sure to check out the NBA DFS advice, player rankings, stacks, and top daily Fantasy basketball picks from SportsLine's Mike McClure.

McClure is a DFS professional with more than $2 million in career winnings. He's also a predictive data engineer at SportsLine who uses a powerful prediction model that simulates every minute of every game 10,000 times, taking factors like matchups, statistical trends and injuries into account. This allows him to find the best NBA DFS values on sites like DraftKings and FanDuel and create optimal lineups that he shares only over at SportsLine. They're a must-see for any NBA DFS player.

On Monday, McClure highlighted Pistons point guard Cade Cunningham as one of his top picks in his NBA DFS player pool on both sites. The result: Cunningham had a triple-double with 17 points, 11 rebounds and 11 assists, returning 50.8 points on DraftKings and 43.7 points on FanDuel for NBA DFS lineups. Anybody who included him in their lineups was well on the way to a profitable day.

McClure has turned his attention to NBA action on Wednesday and locked in his top daily Fantasy basketball picks. You can only see them by heading to SportsLine.

Top NBA DFS picks Wednesday, November 6

For Wednesday, one of McClure's top NBA DFS picks is Lakers forward LeBron James, who is listed at $9,000 on DraftKings and $9,400 on FanDuel. The 20-time All-Star has a resume that compares to any player in the history of the sport, but even in his 22nd season, James isn't performing like your typical player nearing the end of his career. James averaged 25.7 points in his 20th straight season averaging at least 25 points last year. He played 35.3 minutes per game, which was tied for the fourth-most in the league despite finishing the year at 39 years old.

James is averaging 21.9 points, 6.9 rebounds and 7.7 assists through seven games this year, and he has at least 10 assists in back-to-back contests. James neared his 139th triple-double on Monday with 20 points, eight rebounds and 11 assists in 40 minutes against the Pistons. James is still playing significant minutes, and with the Lakers losing three of their last four games, McClure expects a focused performance and high usage from James to outperform his lofty price tag.

Another part of McClure's optimal NBA DFS strategy includes rostering Nuggets point guard Russell Westbrook ($5,000 on DraftKings and $6,400 on FanDuel). Westbrook had 21 points, six rebounds and six assists over 34 minutes against the Raptors on Monday. It was his season-high in minutes and his second straight 30-minute game as Denver will need to ask more of the 35-year-old during this current stretch.

The Nuggets will be without Jamal Murray (concussion) and Aaron Gordon (calf) on Wednesday. Murray didn't play against Toronto, and Gordon left after just four minutes, so although Westbrook expected more playing time before the Raptors' contest, the addition of Gordon's injury put significantly more responsibility on Westbrook to produce. The nine-time All-Star has been an impactful palyer for daily Fantasy basketball players throughout his career with the ability to score, rebound and assist. With an expanded role on Wednesday, McClure expects that to be showcased again. See McClure's other NBA DFS picks right here.

How to set your NBA DFS lineups for Wednesday, November 6

McClure is also targeting a player who could go off for massive numbers on Wednesday because of a dream matchup. This pick could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who it is here.

Who is DFS pro Mike McClure putting in his optimal NBA DFS lineups for Wednesday? Visit SportsLine now to see optimal NBA DFS picks, rankings, advice, and stacks, all from a professional DFS player who has over $2 million in career winnings, and find out.