Lions vs. Seahawks odds, line, spread, prediction: Monday Night Football picks from NFL model on 188-130 roll

SportsLine's model has simulated Seattle Seahawks vs. Detroit Lions on Monday Night Football 10,000 times

The Seattle Seahawks (3-0) will visit the Detroit Lions (2-1) in an NFC battle on Monday Night Football. Mike Macdonald has come out on fire as the new head coach in Seattle. In Week 3, the Seahawks dominated the Miami Dolphins, securing a 24-3 win. The Lions were hit with a loss in Week 2, but bounced back last week, outlasting the Arizona Cardinals, 20-13. 

Kickoff from Ford Field in Detroit is set for 8:15 p.m. ET. Detroit is a four-point favorite in the latest Seahawks vs. Lions odds via SportsLine Consensus, while the over/under for total points scored is 47. Before locking in any Seahawks vs. Lions picks, make sure to check out the NFL predictions and betting advice from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 4 of the 2024 NFL season on an incredible 188-130 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 42-22 roll on top-rated NFL picks since Week 7 of 2022.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has simulated Seahawks vs. Lions 10,000 times and just revealed its coveted NFL picks and Lions vs. Seahawks betting predictions. You can head to SportsLine now to see the model's picks. Here are several NFL odds and NFL betting lines for the spread, money line and over/under for Lions vs. Seahawks:

• Lions vs. Seahawks spread: Detroit -4
• Lions vs. Seahawks over/under: 47 points
• Lions vs. Seahawks money line: Detroit -202, Seattle +167
• SEA: Seahawks have covered the 1H spread in eight of their last 11 away games 
• DET: Lions have covered the spread in 16 of their last 21 games
• Lions vs. Seahawks picks: See picks at SportsLine

Why the Lions can cover

The Lions have a dynamic offense that is well-balanced. Detroit ranks fourth in the NFL in total offense (399.7) and rushing offense (163) but seventh in passing offense (236.7). The dynamic duo at running back of David Montgomery and Jahmyr Gibbs is explosive.

Montgomery runs with power and builds up speed when getting downhill. The Iowa State product is ninth in the NFL in rushing yards (231) and tied for third in rushing touchdowns (3). Last week, the 27-year-old had 23 carries for 105 yards and a touchdown. Gibbs is more explosive and has secure hands as a pass-catcher. The Alabama product logged 207 rushing yards, 76 receiving yards, and two scores. See who to back at SportsLine.

Why the Seahawks can cover

Seattle's offense has been consistent through the first three games. The Seahawks' aerial attack is in a groove, led by quarterback Geno Smith. This unit is ranked eighth in the league in total offense (344), third in passing offense (246.7), and ninth in scoring offense (24.3). 

Smith is a fearless passer in the pocket and owns the arm talent to push the ball downfield. The West Virginia product is third in the NFL in passing yards (787) with three passing touchdowns and completing 74% of his throws. In Week 2 versus the New England Patriots, Smith was 33-of-44 for 327 yards and a one passing touchdown. See who to back at SportsLine.

How to make Lions vs. Seahawks picks

SportsLine's model is leaning Over on the total, projecting the teams to combine for 50 points. The model also says one side of the spread has all the value. Head to SportsLine to see its NFL picks. 

So who wins Seahawks vs. Lions on Monday Night Football, and which side of the spread has all the value? Visit SportsLine now to see which side of the Seahawks vs. Lions spread to back, all from the model that has returned well over $7,000 on top-rated NFL picks, and find out.