Tennessee vs. Oklahoma odds, prediction, spread: 2024 college football Week 4 picks from expert on 15-6 roll

SportsLine expert Emory Hunt revealed his CFB picks for the Oklahoma Sooners vs. Tennessee Vols on Saturday

No. 15 Oklahoma (3-0) will try to slow down No. 6 Tennessee (3-0) when the teams meet in an SEC opener on Saturday night. The Sooners picked up blowout wins over Temple and Tulane while sneaking past Houston two weeks ago. They are playing in their first season in the SEC and are wrapping up a season-opening four-game homestand. Tennessee, coached by former OU quarterback and assistant coach Josh Heupel, has blown out each of its first three opponents, setting a modern-era school-record with 71 points in its shutout win over Kent State last week.

Kickoff from Gaylord Family-Oklahoma Memorial Stadium in Norman is set for 7:30 p.m. ET. Tennessee is a 6.5-point favorite in the latest Oklahoma vs. Tennessee odds from SportsLine consensus, despite Oklahoma opening as a 4.5-point favorite in the look-ahead line. The over/under for total points scored is 56.5. Before making any Tennessee vs. Oklahoma picks, make sure you check out what SportsLine expert, Emory Hunt, has to say.

Hunt is the founder and CEO of Football Gameplan, which has been supplying analysis of all levels of football since 2007, and a former running back at Louisiana-Lafayette. He knows the game from a player's perspective. 

Hunt's dedication to analysis of all levels of college and professional football helped go 93-78-5 (+777) on all college football picks in 2023. He's also 15-6 (+837) on his last 21 sides in Tennessee games. Anyone who has followed him is way up.

Now Hunt has set his sights on Oklahoma vs. Tennessee and just locked in his picks and CFB predictions. You can head to SportsLine now to see Hunt's picks. Here are several college football odds and betting lines on the spread, money line and over/under for Tennessee vs. Oklahoma:

• Tennessee vs. Oklahoma spread: Tennessee -6.5
• Tennessee vs. Oklahoma over/under: 56.5 points
• Tennessee vs. Oklahoma money line: Tennessee -254, Oklahoma +204
• OU: The Sooners are 10-0 in their last 10 home games    
• TENN: The Vols have covered the spread in four of their last five games
• Tennessee vs. Oklahoma picks: See picks at SportsLine

Why Oklahoma can cover

Oklahoma has not been a touchdown underdog at home since 1998, and the Sooners will have a rowdy crowd on hand for this game. Sophomore quarterback Jackson Arnold has thrown for 484 yards and seven touchdowns while rushing for a team-high 159 yards and two touchdowns. He is backed up by an elite defense that is allowing 11.3 points per game, has yet to allow a rushing touchdown and has forced 10 turnovers.

Wide receiver Nic Anderson, who caught 31 passes for 798 yards and 10 touchdowns last season, has been dealing with lingering injuries since fall camp and is expected to return on Saturday. Oklahoma is 9-6 against the spread in 15 home games under coach Brent Venables, who is in his third season in Norman. The Sooners have never been home underdogs under Venables, and this is Tennessee's first true road game this season. See who to back at SportsLine. 

Why Tennessee can cover

Tennessee is off to a perfect start this season, easily covering the spread in all three of its blowout wins. The Vols lead the nation in scoring at 61.0 points per game, with running back Dylan Sampson racking up nine touchdowns while averaging 119 rushing yards per game. Redshirt freshman quarterback Nico Iamaleava has been able to rest in the second half of all three games, but he has still thrown for 698 yards and six touchdowns.

The Vols have arguably been just as impressive defensively, holding opponents to just 4.3 points and 160.7 yards per game. They are facing an Oklahoma offensive line that has already allowed 11 sacks and has not opened up many running lanes. The Sooners are dealing with significantly more injury issues than a relatively healthy Tennessee team as well. See who to back at SportsLine.

How to make Oklahoma vs. Tennessee picks

Hunt has analyzed this matchup from every angle. He's found a critical x-factor that has him jumping on one side of the spread. See what it is at SportsLine.

Who wins Tennessee vs. Oklahoma, and what critical x-factor makes one side of the spread a must-back? Visit SportsLine now to see which side of the spread you need to jump on Saturday, all from the expert who is his college football picks last year and is 15-6 (+837) on his last 21 sides in Tennessee games.