Scientists pinpoint thousands of gene variants linked to breast and ovarian cancer risk
Scientists have pinpointed thousands of genetic changes in a gene that may increase a person's risk of developing breast and ovarian cancer, paving the way for better risk assessment and more personalised care.
Study may represent a possible surgery-free strategy for managing cataracts
Researchers at the National Institutes of Health (NIH) and their collaborators have identified a protein, known as RNF114, that reverses cataracts, a clouding of the eye's lens that occurs commonly in people as they age.
Clinical trial finds pomalidomide effective for treating rare bleeding disorder
A clinical trial supported by the National Institutes of Health (NIH) was stopped early after researchers found sufficient evidence that a drug used to treat bone marrow cancer and Kaposi sarcoma is safe and effective in treating hereditary hemorrhagic telangiectasia (HHT), a rare bleeding disorder that affects 1 in 5,000 people worldwide.
Direct breastfeeding boosts microbial transfer to very-low-birth-weight infant guts
Researchers found that 30-40% of the very-low-birth-weight infant's gut microbiota came from the mother’s milk, and direct breastfeeding enhances microbial transmission despite antibiotic exposure.
New tool unveils dynamic changes in brain extracellular matrix
Between and around the billions of neurons in the human brain is an equally vital scaffold, the extracellular matrix (ECM).
Leptin variations may influence brain health and dementia development
New research is more closely linking obesity to dementia. Higher levels of leptin, a hormone that helps maintain normal body weight, is associated with better signal-transmitting brain white matter in middle-aged adults, according to a study by The University of Texas Health Science Center at San Antonio (UT Health San Antonio).
New Alzheimer’S Studies Reveal Disease Biology, Risk For Progression, And The Potential For A Novel Blood Test
The failure to diagnose Alzheimer's disease, the most common form of dementia in the elderly, at an early stage of molecular pathology is considered a major reason why treatments fail in clinical trials. Previous research to molecularly diagnose Alzheimer's disease yielded "A/T/N" central biomarkers based on the measurements of proteins, β-amyloid ("A") and tau ("T"), and "N" encompassing neurodegeneration. A/T/N can be measured in brain tissue, by in vivo brain imaging techniques, and by analysis of cerebrospinal fluid and plasma.
Researchers uncover receptor that dampens sensory input
Signals in our brain are not always processed in the same way: Certain receptors modulate these mechanisms, influencing our mood, perception, and behavior in various ways. One of these is the 5-HT2A receptor, which has a recently discovered unique characteristic.
Study finds thousands of food-contact chemicals in humans, raising safety concerns
A recent study reveals that 25% of known food-contact chemicals (FCCs) are present in humans, with significant gaps in hazard data for many chemicals, highlighting potential health risks.
Cancer drug shows promise for treating rare bleeding disorder
A clinical trial has demonstrated that the cancer drug pomalidomide is safe and effective in treating hereditary hemorrhagic telangiectasia (HHT), a rare bleeding disorder that impacts more than 1 in 5,000 people worldwide. The trial, led by Keith McCrae, M.D., of Cleveland Clinic and supported by the National Institutes of Health, was stopped early because of these successful findings, and has been published in the New England Journal of Medicine.
IBD increases type 1 diabetes risk, revealing a bidirectional link between the two conditions
Researchers discovered that IBD significantly increases the risk of developing T1D, and this association works both ways, independent of genetics and familial factors. The strongest link was seen in ulcerative colitis patients.
Clinical trial demonstrates effectiveness of drip iron for anemia
Researchers found that a medicine called ferric carboxymaltose given in drip through the vein works faster and better than an iron tablet taken by mouth for the treatment of anemia – and it is as safe as the tablet. The findings were published in Lancet Global Health.
New study shows the effectiveness of alcohol calorie labeling
Just over half of heavier drinkers in England say they would make changes to their drinking if calorie labels for alcohol were introduced, according to a new study by UCL researchers.
Study shows effectiveness of colored disinfectant wipes
A new study published today in the American Journal of Infection Control (AJIC) reports a comparison of hospital room cleanliness using standard disinfectant wipes versus wipes with a color additive that allows users to see which surfaces have been sanitized. With the color additive, rooms were 69.2% cleaner and were able to be cleaned in slightly less time compared to cleaning with standard wipes. The study was performed at Griffin Hospital in Derby, Conn.
IIM Raipur, Academy of Digital Sciences launch 4th batch of health programmes
IIM Raipur and Digital Health Sciences have announced the fourth batch of the PGCPDH and DPDH programmes.
Abortion clinics — and patients — are on the move, as state laws keep shifting
Soon after a series of state laws left a Planned Parenthood clinic in Columbia, Missouri, unable to provide abortions in 2018, it shipped some of its equipment to states where abortion remained accessible.
Hypoxia's hidden role in boosting anti-cancer immunity
In the complex landscape of cancer, tumors create their own microenvironment, often marked by low oxygen levels, a condition known as hypoxia.
Multiple myeloma drug shows efficacy in treating rare bleeding disorder
A drug approved for treating the blood cancer multiple myeloma may offer a safe and effective way to reduce the risk of severe nosebleeds from a rare but devastating bleeding disorder.
Karnataka has third highest number of rural PHCs in country, but paucity of doctors is a major issue
Karnataka ranks third in rural PHCs but faces shortage of medical staff, and needs to focus on enhancing human resources in healthcare.
Highest number of men in decade begin priesthood studies
A total of 21 men are set to begin studying for the priesthood, the highest number to come forward for the role in over a decade.
COYA 302 combination therapy tames brain inflammation in mice
COYA 302, a combination therapy in development for Parkinson's, reduced excessive inflammation and immune cell activation in a mouse model.
COYA 302 combination therapy tames brain inflammation in mice
COYA 302, a combination therapy in development for Parkinson's, reduced excessive inflammation and immune cell activation in a mouse model.
Researchers discover how patients can get addicted to levodopa
A study has found a mechanism underlying an addiction-like side effect — dopamine dysregulation syndrome — of the Parkinson's drug levodopa.
The University of Leeds leads the way for Indian students
“We are organising a health research convention, which comprises a couple of workshops, community-based learning, and also cardiac care. We also included a one-day seminar on medical education, how medical education has evolved in India and the U.K., and what we can learn from each other” said Dr. Piruthivi Sukumar Dean of the International Faculty of Medicine & Health, University of Leeds during his interaction with The Hindu.
IISc researchers come up with solutions to reduce presence of heavy metals in groundwater
IISc researchers develop nanomaterial to reduce chromium in groundwater, offering on-site remediation solution for heavy metal contamination.
New method identifies biomarkers in wastewater using origami-paper sensors
Researchers at Cranfield University have developed an innovative new method for identifying biomarkers in wastewater using origami-paper sensors, enabling the tracking of infectious diseases using the camera in a mobile phone.
Phase 1 trial shows safety and efficacy of personalized vaccine for lymphoplasmacytic lymphoma
A team of researchers from City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the U.S., and The University of Texas M.D. Anderson Cancer Center, have reported safety and efficacy results from a Phase 1 trial that featured a personalized vaccine to treat lymphoplasmacytic lymphoma, a rare and slow-growing type of blood cancer, according to a study published recently in Nature Communications.
Study reveals impact of human breast milk on infant microbiome and respiratory health
Human breast milk regulates a baby's mix of microbes, or microbiome, during the infant's first year of life. This in turn lowers the child's risk of developing asthma, a new study shows.
Cellular sludge around hunger neurons linked to worsening diabetes and obesity
Investigating ECM changes in the hypothalamus reveals mechanisms behind insulin resistance, offering insights into obesity and metabolic disease treatment.
Nanoparticle-based remediation of chromium-contaminated water shows high efficiency
Groundwater is an essential source of drinking water across the country. However, heavy metal contamination in groundwater presents a significant health hazard. Researchers at the Indian Institute of ...
Urban meteorology study likely in Vijayawada, says Union Ministry of Earth Sciences
MoES advisor Kamaljit Ray discusses urban meteorology study in Vijayawada to enhance forecasting models for extreme weather events.
Global fight against antimicrobial resistance sees surge in deaths among older adults
Comprehensive study estimates the global antimicrobial resistance (AMR) burden from 1990 to 2021, identifying significant age and regional disparities. It highlights future AMR death projections and underscores the importance of prevention and new antibiotic development.
last updated on 20 Sep 00:51